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The parameter describes an oxygen metabolism speed. Its physical meaning – oxygen demand speed in ml/sec. It is included in the equation system describing oxygen metabolism as the value RO₂

(4)

In the equation (4) the value of tissue oxygen delivery gO₂ is proportional to values of tissue blood flow Q and arteriovenous oxygen difference AO₂ - VO₂. In its turn a change speed of venous oxygen concentration is proportional to the difference between tissue oxygen delivery and oxygen demand (5)

(5)

A change speed of oxygen debt is proportional to the difference between tissue oxygen demand and tissue oxygen delivery (6)

(6)

The parameter RO₂ is used for modelling of pathologic mode "exercise stress". The main characteristic of this mode is an increase of its value in comparison with the normal one.